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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodePINP
Method

Roche Cobas e411 - 2 site sandwich (immunometric)

Diagnostic Use / Indications

P1NP (total procollagen type 1 N-terminal propeptide) is the preferred marker for bone formation. It is a specific indicator of type 1 collagen deposition. It is released as a trimeric structure, but degrades to a monomer. The Elecsys assay detects both, ie. total P1NP.

It is increased in states of high bone turnover and hence may be of value for assessing the response to treatment of osteoporosis and Paget's disease.

Has been reported to be a marker for bone metastases of several types of carcinoma.

External Price$61.07(Exclusive of GST)
  

Specimen Collection

 
Patient SpecimenEDTA(Lavender),Heparin(Green) or serum(Red), 0.9mL
Paediatric Specimen0.3mL
Sample Delivery to LabAmbient
  

Instructions for Referral to CHLabs

 
Aliquot Instructions0.9 mL plasma preferred. 0.3 mL is the absolute minimum. Store frozen.
Aliquot Transport to CHLFrozen
  

CHLabs Laboratory

 
DepartmentEndocrinology Laboratory
Contact Details Email Email
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Contact Phone Number(03) 3640886 | x80886
Test Availabilityweekly
Reference Interval

Female

Age (yrs)

mg/L

 

<1

900-1800

 

1 - 2

500-1500

 

3 - 10

300-1000

 

10 - <14

140–1200

 

14 - <18

40–460

 

18 - <25

20–110

 

25 - <35

20–85

 

35+ premenopausal

15–60

 

35+ postmenopausal

20-115

Male

<1

830-1850

 

1 - 2

400-1500

 

3 - <12

300-900

 

12 - <17

220-1600

 

17 - <18

80–480

 

18 - <20

60–220

 

21 - <25

35–140

 

25+

20-85

Additional Information

Evaluation of a Fully Automated Serum Assay for Total N-Terminal Propeptide of Type I Collagen in Postmenopausal Osteoporosis Patrick Garnero, Philippe Vergnaud and Nicholas Hoyle. Clinical Chemistry 54: 188-196, 2008

Delphic Number Test Number8382

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