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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodeTS15
Method

DNA extracted from FFPE tissue is analysed using the Illumina TruSight Tumor 15 assay (TS15). This assay uses next-generation sequencing (NGS) technology to provide a comprehensive assessment of 15 genes that are commonly mutated in solid tumors. Details of the genes and regions covered by the TS15 assay are shown below.

External Price$582.09(Exclusive of GST)
  

Specimen Collection

 
Specimen Collection Protocols

6x 5-micron unstained FFPET slides (non-adhesive/uncharged preferred) PLUS 1x H&E stained slide with the tumour area marked (minimum 30% tumour content is required).

Patient SpecimenFFPET.
  

CHLabs Laboratory

 
DepartmentBiochemistry - Molecular Oncology
Contact Details Email Email
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Contact Phone Number03 3786 008 / x86008
Turnaround Time14 days from receipt of specimen. Please contact the laboratory to discuss priority for urgent samples.
Reference Interval

 Genes/regions included in the Tumor-15 test

Gene

Region covered

Cancers associated

AKT1

Exon 3 (partial)

Breast

BRAF

Exon 15 (partial)

Melanoma, colon, lung

EGFR

Focal amplification, exons 12 (partial), 18, 19, 20, 21 (partial)

Lung

ERBB2 (HER2)

Focal amplification, exons 14 (partial), 17, 18, 19, 20 (partial), 21 (partial), 24, 26

Breast, lung

FOXL2

Exon 1 (partial)

Ovary

GNA11

Exon 5 (partial)

Melanoma

GNAQ

Exon 5 (partial)

Melanoma

KIT

Exons 8, 9, 10, 11, 13, 14, 17, 18

Gastric, melanoma

KRAS

Exons 2 (partial), 3 (partial), 4

Colon, gastric, lung

MET

Focal amplification

Lung, colon, gastric

NRAS

Exons 2 (partial), 3 (partial), 4

Colon

PDGFRA

Exons 12, 14, 18

Gastric, melanoma

PIK3CA

Exons 10, 21

Lung, breast, prostate

RET

Exon 16

Lung

TP53

All coding exons

Lung, melanoma, ovary, colon

Interpretation

NOTE: This method does not distinguish between germline and somatic variants. If a germline variant is suspected, testing of the variant on a peripheral blood sample is recommended.

Delphic Number Test NumberTS15

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