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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodeAVP
Method

Extracted RIA

Diagnostic Use / Indications

Severe hyponatraemia - especially if "ectopic ADH" syndrome is suspected.
In some difficult cases of hypernatraemia or diabetes insipidus.
Note: Diagnosis of diabetes insipidus is usually possible by careful evaluation of water balance, and sequential changes of urine and plasma osmolality after water restriction, and exogenous vasopressin administration (eg Miller test).

External Price$67.81(Exclusive of GST)
  

Specimen Collection

 
Pre-Testing Requirements

Patients should be non-stressed. AVP increases if patient faints.
All patients warranting AVP assays should have serum osmolality determined (as well as plasma sodium) at the time of blood sampling for AVP. Urine osmolality is also helpful for interpretation.

Specimen Collection Protocols

Blood 7 mL EDTA

Patient SpecimenBlood 7 mL EDTA(Lavender). Serum not acceptable
Sample Delivery to LabAmbient
  

Instructions for Referral to CHLabs

 
Aliquot Instructions2.5 mL Plasma, frozen.
Aliquot Transport to CHLFrozen
  

CHLabs Laboratory

 
DepartmentEndocrinology Laboratory
Contact Details Email Email
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Contact Phone Number(03) 364 0885 | x80885
Test AvailabilityBatched fortnightly
Turnaround Time7 - 21 days (3 day minimum for urgent requests
Reference Interval

Male and Female, no drugs: < 5 pmol/L

Interpretation

Depends on serum osmolality as well as "volume" status. Severe dehydration, hypotension and/or stress (especially nausea and vomiting) will increase AVP. Low serum osmolality will decrease AVP if volume status is normal. The assay detection limit is approximately 0.2pmol/L. Therefore overnight fluid deprivation may be necessary to aid in interpretation of AVP results.

Uncertainty of Measurement

+/- 0.4 < 1.2 pmol/L

+/- 34% >1.2 pmol/L

Additional Information

Assay is suitable for all species other than pigs.

Delphic Number Test Number6516

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