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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodeCPEP
Method

Roche Cobas e411

Diagnostic Use / Indications

May be of value in the assessment of residual pancreatic function in insulin treated diabetics, diagnosis of insulinoma and for investigation for covert insulin administration. It is suggested that an endocrinologist be consulted.

External Price$39.81(Exclusive of GST)
  

Specimen Collection

 
Pre-Testing Requirements

Fasted overnight. Fasting and 2 hour postprandial plasma glucose levels are useful INITIAL screening tests. Please send these results with C-peptide.

Specimen Collection Protocols

Avoid haemolysis.

Patient SpecimenBlood 2 mL EDTA(Lav)or Lithium hep (Green)
Sample Delivery to LabOn water/ice slurry if haemolysis likely.
  

Instructions for Referral to CHLabs

 
Aliquot Instructions>0.5 mL Plasma or Serum. Frozen
Aliquot Transport to CHLAmbient for up to 5 days if no hemolysis, otherwise frozen.
  

CHLabs Laboratory

 
DepartmentEndocrinology Laboratory
Contact Details Email Email
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Contact Phone Number(03) 3640886 | x80886
Test AvailabilityTwice weekly
Turnaround Time3 - 7 days
Reference Interval

350 - 750 pmol/L (fasting, BMI <25)

Interpretation

A deficient plasma C-peptide response to a defined protein/carbohydrate meal is seen in diabetes mellitus. For most clinical purposes the 24-hr urinary C-peptide excretion gives an adequate and more convenient index of endogenous pancreatic function. Excessive urinary C-peptide excretion is seen in insulinoma. Deficient C-peptide excretion is seen in diabetes mellitus and in hypoglycaemia due to the administration of exogenous insulin.

Additional Information

Measure glucose at the same time.

At room temperature, C-peptide is sensitive to hemolysis, and the rate of C-peptide loss increases with the degree of hemolysis. For example, at a level of 0.8g Hb/L, 10% of C-peptide is lost after 24 hours at room temperature.

C-peptide in plasma is not stable long-term at -20o. Loss is of the order of 2% per month. Stable at -40o or lower.

Delphic Number Test Number7650

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