JAK2 Exon 12 Mutation Screen
Test Identifier Information | |
| Registration Code | MONC |
| Method | PCR using primers that span the region commonly associated with acquired JAK2 exon 12 mutations, followed by fragment analysis using capillary electrophoresis, and allele-specific PCR. Approximately 80% of all currently known JAK2 exon 12 mutations are detected by this method including those commonly associated with polycythaemia. |
| Diagnostic Use / Indications | Negative for JAK2 V617F mutation. Low serum erythropoietin level. Most patients present with significantly raised hemoglobin levels, and a distinctive histological appearance of the bone marrow. |
| External Price | $679.47(Exclusive of GST) |
Specimen Collection | |
| Pre-Testing Requirements | Negative for JAK2 V617F mutation. Low serum erythropoietin level |
| Patient Specimen | 5-10ml PB in EDTA or 1 ml BM |
CHLabs Laboratory | |
| Department | Biochemistry - Molecular Oncology |
| Contact Details |
Email
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| Contact Phone Number | 03 3786 008 / x86008 |
| Turnaround Time | 20 working days |
| Uncertainty of Measurement | Limit of detection approximately 1 abnormal cell in 20. Approximately 80% of all currently known JAK2 exon 12 mutations are detected by this method including those commonly associated with polycythaemia. |
| Delphic Number Test Number | 8389 |
