HLA-B27
Test Identifier Information | |
| Registration Code | B27 |
| Method | The assay uses a real-time PCR method for the detection of the HLA-B27 genotype using allele-specific primers combined with a TaqMan fluorescent minor groove binder (MGB) probe. |
| Diagnostic Use / Indications | Ankylosing spondylitis (AS) is a chronic inflammatory disease affecting the musculoskeletal system and characterised by absence of ANA and rheumatoid factor. The association between AS and HLA-B27 is so pronounced that the presence of B27 can be used as a diagnostic aid very early in disease development. 90-95% of AS patients are HLA-B27 positive compared with only 5-8% of the normal (Caucasian) population. |
| External Price | $59.80(Exclusive of GST) |
Specimen Collection | |
| Patient Specimen | 4.0mL EDTA (Lavender) blood |
| Paediatric Specimen | 0.5 mL - 1 mL EDTA blood |
| Sample Delivery to Lab | As soon as practicable (may be refrigerated overnight or up to 72 hours before sending) |
| Aliquot Transport to CHL | Ambient or refrigerated |
CHLabs Laboratory | |
| Department | Biochemistry - Molecular Pathology |
| Contact Details |
Email
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| Contact Phone Number | 03 3640 548 |
| Test Availability | 9am-5pm Mon-Fri |
| Turnaround Time | 28 days |
| Additional Information | Clotted samples unacceptable. |
| Delphic Number Test Number | 6992 |
