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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodeOHPR
Method

liquid chromatography mass spectrometry (LCMSMS)

Diagnostic Use / Indications

17-OHP is a steroid that is metabolised to make cortisol; it is a substance used by the body to make cortisol

The 17-OHP may be requested  when a child has ambiguous genitalia and may be repeated if the screening test is elevated to confirm the initial results. A 17-OHP test may be requested whenever an infant has signs and symptoms of adrenal insufficiency or experiences salt-wasting crises

An infant with CAH may also have ambiguous genitalia, virilisation, acne, or pubic hair. This test may sometimes be requested in older children or in adults when the milder form of CAH (late-onset) is suspected. The 17-OHP test may also be conducted when a girl or woman is experiencing symptoms such as: Hirsutism, Lack of or irregular periods (menses), Virilization and infertility.

 

External Price$59.80(Exclusive of GST)
  

Specimen Collection

 
Specimen Collection Protocols

Serum, Red top tube only. SST, LiHep tubes unacceptable.

Patient Specimen1 mL Red top tube. SST, LiHep tubes unacceptable.
Paediatric Specimen500 uL Red top tube. SST, LiHep tubes unacceptable
Sample Delivery to LabFrozen
  

Instructions for Referral to CHLabs

 
Aliquot Instructions600 uL serum, paediatric absolute minimum 300 uL serum. Freeze.
Aliquot Transport to CHLFrozen
  

CHLabs Laboratory

 
DepartmentBiochemistry - Steroid Laboratory
Contact Details Email Email
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Contact Phone Number(03) 3640886 | x80886
Test AvailabilityBatched weekly (analysed on Friday)
Turnaround Time 7 days
Reference Interval

REFERENCE INTERVALS
 
0 to <3 Months
Male & Female     <9.0 nmol/L
3 Months to <10 years
Male & Female     <3.5 nmol/L
1o years and older
Male = <6.0 nmol/L , Female <9.0 nmol/L

Interpretation

17-OHP Post Synacthen
 
 
Basal (nmol/L)
60 min Post (nmol/L)
Interpretation
0 -9.0
<9.0
Normal Genotype
3 -400
90 -400
Probable CAH, consider endocrine review
 
2 -50
Possible heterozygote carrier for CAH

Additional Information

Endocrine & Steroid Laboratory Phone 03 3640 848

For results please contact Canterbury Health Laboratories ph. 03 364 0300.

Reference.

Taylor DR, Ghataore L, Couchman L, et al. A 13-Steroid Serum Panel Based on LC-MS/MS: Use in Detection of Adrenocortical Carcinoma. Clin Chem. 2017;63(12):1836‐1846. doi:10.1373/clinchem.2017.277624
Delphic Number Test Number8049

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