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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodeLH
Method

Two-site immunometric assay on Roche Cobas e411 analyser.

Diagnostic Use / Indications

Investigation of primary and secondary amenorrhoea, and/or gonadal failure.

Assessment of hypothalamic-pituitary function. Note that repeated sampling may be necessary in order to demonstrate impaired LH secretion because of oscillations in LH values during the day. In postmenopausal women there is less difficulty, as resting values are higher than in pre-menopausals. A pre-menopausal value in postmenopausal woman is suggestive of hypothalamic-pituitary disease. In males a low plasma testosterone with low or “normal” LH values is suggestive of hypothalamic or pituitary disease.

Detection of pre-ovulatory surge – either spontaneous or in response to clomiphene citrate. A mid-cycle LH peak precedes ovulation by 24 – 48 hours.

Polycystic ovary syndrome – some but not all of these patients (approx. 50%) may have tonically increased plasma LH levels. (FSH is normal).

External Price$11.27(Exclusive of GST)
  

Specimen Collection

 
Pre-Testing Requirements

Time of sampling is not critical (except for some research studies). Details of age, gender, last menstrual period and medications, (especially oral contraceptive or sex steroids) are essential. To avoid confusion with the mid-cycle LH peak it may be necessary to take two samples at least two days apart.

Patient SpecimenBlood, 4mL tube. Red, Green, purple top.
Sample Delivery to LabAmbient
  

Instructions for Referral to CHLabs

 
Aliquot InstructionsPreferably >0.5 mL serum or plasma. Minimum 0.2 mL.
Aliquot Transport to CHLAmbient within 3 days or else 4C
  

CHLabs Laboratory

 
DepartmentEndocrinology Laboratory
Contact Details Email Email
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Contact Phone Number(03) 3640886 | x80886
Test AvailabilityMon - Fri, business hours only
Turnaround Time1 - 4 days
Reference Interval

0-9 yrs              0-2.5 IU/L

10-15 yrs           Levels rise during puberty towards adult range

 

Adult male        2-9 IU/L

 

Adult female      Follicular                       2-8 IU/L

                        Mid cycle                      10-75 IU/L

                        Luteal                           2-8 IU/L

                        Post menopause            >15 IU/L

                        Antenatal                      <1 IU/L

 

Interpretation

During the menopausal transition, which may last several months or longer, values of LH may fluctuate considerably.

Method changed from Beckman Coulter Access to Roche Elecsys on 13/4/2011.

Additional Information

Reference intervals exclude subjects on oral contraceptives or HRT.

Delphic Number Test Number6547

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