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Test Identifier Information

 
Registration CodeSMBH
Method

Flow Cytometry is the preferred method for PNH testing.

External Price$347.20(Exclusive of GST)
  

Specimen Collection

 
Specimen Collection Protocols

Please indicate if the patient has received RBC transfusion within the previous three months.

Patient Specimen2 x 5ml EDTA(Lavender) blood
Paediatric Specimen1 x 5ml EDTA(Lavender) blood
Sample Delivery to LabRoom temperature within 48 hours.
  

Instructions for Referral to CHLabs

 
Aliquot InstructionsMinimum aliquot 1 x 5ml EDTA blood. Preferred aliquot 2 x 5ml EDTA blood. Bone Marrow not accepted. Samples must be stored at room temperature and delivered to the laboratory within 48 hours.
Aliquot Transport to CHLRoom temperature ASAP.
  

CHLabs Laboratory

 
DepartmentHaematology - Surface Markers
Contact Details Email Email
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Contact Phone Number(03) 3640 917 x80917
Test AvailabilityMon - Fri business hours only. (Samples should be received by lab before 12 noon on Fridays.)
Turnaround Time1 - 3 days.
Interpretation

Granulocytes are tested for the GPI linked antigen CD24 and FLAER (fluorescent aerolysin - a marker for the GPI anchor). Monocytes are tested for the GPI linked antigen CD14 and FLAER. Red blood cells are tested for the the GPI linked antigen CD59.  

Cells negative or weakly positive for GPI linked antigens and/or FLAER indicates the presence of a PNH clone. 

Additional Information

Flow cytometry is the preferred method for PNH screening.


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